OVERVIEW

Testosurge® is a natural, highly standardized ingredient proven in clinical studies to significantly increase total and biologically active free testosterone. Designed for products to boost testosterone, increase performance, and support healthy sexual function.
  • Works from the first dose
  • Backed by published clinical studies
  • Unique mechanism of action

Specifications:

Marker Glycosides not less than 80%

VARIANTS

Powder

Capsule, Tablet, Gummies, Oral Strips, Protein Powders

Debittered Version

Ready to Drink formulation

VARIANTS

Powder

Capsule, Tablet, Gummies, Oral Strips, Protein Powders

Debittered Version

Capsule, Tablet, Gummies, Oral Strips, Protein Powders

OVERVIEW

Testosurge® is a natural, highly standardized ingredient proven in clinical studies to significantly increase total and biologically active free testosterone. Designed for products to boost testosterone, increase performance, and support healthy sexual function.
  • Works from the first dose
  • Backed by published clinical studies
  • Unique mechanism of action

Specifications:

Marker Glycosides not less than 80%

VARIANTS

Powder

Capsule, Tablet, Gummies, Oral Strips, Protein Powders

Debittered Version

Capsule, Tablet, Gummies, Oral Strips, Protein Powders

HEALTH BENEFITS

Benefits of HEALTHY TESTOSTERONE

May help support sexual function | Improved body composition | May help in weight management |
May help with healthy aging

USP

  • GRAS certified
  • Made from DNA authenticated raw material
  • 100% traceability to the raw material
  • 100% natural & safe ingredient
  • Certified Informed Ingredient
  • Certified Strong Science
  • Highly standardized for accurate dosing
  • Water-soluble, Halal, Kosher, Vegan
  • Non-GMO project verified
  • Clean extraction
  • NPN and TGA approved
  • California Proposition 65 compliant
  • ETO free

USP

  • GRAS certified
  • Made from DNA authenticated raw material
  • 100% traceability to the raw material
  • 100% natural & safe ingredient
  • Certified Informed Ingredient
  • Certified Strong Science
  • Highly standardized for accurate dosing
  • Water-soluble, Halal, Kosher, Vegan
  • Non-GMO project verified
  • Clean extraction
  • NPN and TGA approved
  • California Proposition 65 compliant
  • ETO free

SCIENCE

Scenario

Scenario

  • According to research, around 30% of overweight men have Testosterone Deficiency.
  • 38% of men above 40 have testosterone levels below 300 ng/dl.
  • Above the 80-year threshold, more than 50% of men have testosterone levels below 300 ng/dl.
  • As far as diabetes patients go, up to 24% of men have low testosterone levels.
  • Low T-levels are harmful for all aspects, including physical, mental, and social

Reference:

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854084/

Foundation

Foundation

A broad spectrum of systematic reviews and scientific data demonstrated that fenugreek and its extracts improve glycemic and lipid profiles. Fenugreek is known to have antioxidant, anti-carcinogenic, gastro protective, anti-inflammatory, antimicrobial, immunological, anti-obesity, and hepatoprotective effects, and are beneficial to women’s health. Further, previous studies reported that fenugreek improved cognitive functions and Parkinson’s symptoms and showed anti anxiety, antidepressant, and neuroprotective properties. A recent study has reported the beneficial effects of fenugreek and its extract on hormonal-related statuses, such as galactagogue in lactating women and male impotence.

The presence of fenugreek seeds in various traditional medicinal systems is due to their composition of diverse phytochemicals, including Glycosides.

Potential benefits of fenugreek glycosides in testosterone production include: Increased Testosterone Levels:

  • Fenugreek supplementation may lead to an increase in testosterone levels, which could have positive effects on muscle mass, strength, and overall vitality.
  • Enhanced Libido: Fenugreek has been traditionally used as an aphrodisiac, and its potential influence on testosterone levels may contribute to improvements in libido and sexual health.
  • Improved Exercise Performance: Higher testosterone levels may be associated with increased exercise performance and muscle strength, making fenugreek an area of interest for athletes and those involved in physical fitness.
  • Spermatogenesis Support: Testosterone plays a crucial role in spermatogenesis (sperm production), and fenugreek’s potential impact on testosterone levels may have implications for male reproductive health.

Mechanism
of action

Mechanism of Action

Testosurge® is standardized to include a specific combination of steroidal and flavonoid glycosides. The steroidal glycosides in Testosurge® enhance the effectiveness of testosterone by competitively binding with SHBG. When testosterone is released into the bloodstream approximately 60-70% of it binds to SHBG. The steroidal glycosides from Testosurge® binds to SHBG and make testosterone free and bioavailable.

On the other hand, the flavonoid glycosides in Testosurge® play a role in increasing testosterone production. They achieve this by enhancing the expression of the steroidogenic acute regulatory (StAR) protein in Leydig cells. Testosterone is produced within the mitochondria of Leydig cells through steroidogenesis, where the StAR protein facilitates the entry of cholesterol into the mitochondrion.

Testosurge® has demonstrated inhibitory activity against5-alpha reductase and aromatase in cell line studies. 5-alpha reductase is an enzyme responsible for converting testosterone into DHT, while aromatase converts testosterone into Estrogen. This inhibition activity suggests that Testosurge® may help regulate the levels of these hormones in the body.

Additionally, Testosurge® can inhibit PDE5 enzyme which canresult in improved vasodilation and penile blood flow.

Efficacy

Efficacy

Human Clinical Study 1: Effects of Testosurge® supplementation on strength, body composition and hormonal profiles during an 8-week resistance training program.

Result: 500 mg of daily Testosurge®supplementation significantly impacted Body Fat Percentage, Total Testosterone and Bioavailable Testosterone.

Human Clinical Study 2: Effects of Single dose Testosurge® on serum testosterone levels of healthy sedentary male subjects

Result: Single dose of Testosurge® significantly increased Free Testosterone, Bioavailable Testosterone, and Total Testosterone Levels after 10 hours of administration.

SCIENCE

Scenario

Scenario

  • According to research, around 30% of overweight men have Testosterone Deficiency.
  • 38% of men above 40 have testosterone levels below 300 ng/dl.
  • Above the 80-year threshold, more than 50% of men have testosterone levels below 300 ng/dl.
  • As far as diabetes patients go, up to 24% of men have low testosterone levels.
  • Low T-levels are harmful for all aspects, including physical, mental, and social

Reference:

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854084/

Foundation

Foundation

A broad spectrum of systematic reviews and scientific data demonstrated that fenugreek and its extracts improve glycemic and lipid profiles. Fenugreek is known to have antioxidant, anti-carcinogenic, gastro protective, anti-inflammatory, antimicrobial, immunological, anti-obesity, and hepatoprotective effects, and are beneficial to women’s health. Further, previous studies reported that fenugreek improved cognitive functions and Parkinson’s symptoms and showed anti anxiety, antidepressant, and neuroprotective properties. A recent study has reported the beneficial effects of fenugreek and its extract on hormonal-related statuses, such as galactagogue in lactating women and male impotence.

The presence of fenugreek seeds in various traditional medicinal systems is due to their composition of diverse phytochemicals, including Glycosides.

Potential benefits of fenugreek glycosides in testosterone production include: Increased Testosterone Levels:

  • Fenugreek supplementation may lead to an increase in testosterone levels, which could have positive effects on muscle mass, strength, and overall vitality.
  • Enhanced Libido: Fenugreek has been traditionally used as an aphrodisiac, and its potential influence on testosterone levels may contribute to improvements in libido and sexual health.
  • Improved Exercise Performance: Higher testosterone levels may be associated with increased exercise performance and muscle strength, making fenugreek an area of interest for athletes and those involved in physical fitness.
  • Spermatogenesis Support: Testosterone plays a crucial role in spermatogenesis (sperm production), and fenugreek’s potential impact on testosterone levels may have implications for male reproductive health.

Mechanism of action

Mechanism of Action

Testosurge® is standardized to include a specific combination of steroidal and flavonoid glycosides. The steroidal glycosides in Testosurge® enhance the effectiveness of testosterone by competitively binding with SHBG. When testosterone is released into the bloodstream approximately 60-70% of it binds to SHBG. The steroidal glycosides from Testosurge® binds to SHBG and make testosterone free and bioavailable.

On the other hand, the flavonoid glycosides in Testosurge® play a role in increasing testosterone production. They achieve this by enhancing the expression of the steroidogenic acute regulatory (StAR) protein in Leydig cells. Testosterone is produced within the mitochondria of Leydig cells through steroidogenesis, where the StAR protein facilitates the entry of cholesterol into the mitochondrion.

Testosurge® has demonstrated inhibitory activity against5-alpha reductase and aromatase in cell line studies. 5-alpha reductase is an enzyme responsible for converting testosterone into DHT, while aromatase converts testosterone into Estrogen. This inhibition activity suggests that Testosurge® may help regulate the levels of these hormones in the body.

Additionally, Testosurge® can inhibit PDE5 enzyme which canresult in improved vasodilation and penile blood flow.

Efficacy

Efficacy

Human Clinical Study 1: Effects of Testosurge® supplementation on strength, body composition and hormonal profiles during an 8-week resistance training program.

Result: 500 mg of daily Testosurge®supplementation significantly impacted Body Fat Percentage, Total Testosterone and Bioavailable Testosterone.

Human Clinical Study 2: Effects of Single dose Testosurge® on serum testosterone levels of healthy sedentary male subjects

Result: Single dose of Testosurge® significantly increased Free Testosterone, Bioavailable Testosterone, and Total Testosterone Levels after 10 hours of administration.