OVERVIEW
VARIANTS
OVERVIEW
VARIANTS
HEALTH BENEFITS
Benefits of high endurance levels
USP
USP
SCIENCE
Scenario
Scenario
- According to research, around 30% of overweight men have Testosterone Deficiency.
- 38% of men above 40 have testosterone levels below 300 ng/dl.
- Above the 80-year threshold, more than 50% of men have testosterone levels below 300 ng/dl.
- As far as diabetes patients go, up to 24% of men have low testosterone levels.
- Low T-levels are harmful for all aspects, including physical, mental, and social
Reference:
Foundation
Foundation
A broad spectrum of systematic reviews and scientific data demonstrated that fenugreek and its extracts improve glycemic and lipid profiles. Fenugreek is known to have antioxidant, anti-carcinogenic, gastro protective, anti-inflammatory, antimicrobial, immunological, anti-obesity, and hepatoprotective effects, and are beneficial to women’s health. Further, previous studies reported that fenugreek improved cognitive functions and Parkinson’s symptoms and showed anti anxiety, antidepressant, and neuroprotective properties. A recent study has reported the beneficial effects of fenugreek and its extract on hormonal-related statuses, such as galactagogue in lactating women and male impotence.
The presence of fenugreek seeds in various traditional medicinal systems is due to their composition of diverse phytochemicals, including Glycosides.
Potential benefits of fenugreek glycosides in testosterone production include: Increased Testosterone Levels:
- Fenugreek supplementation may lead to an increase in testosterone levels, which could have positive effects on muscle mass, strength, and overall vitality.
- Enhanced Libido: Fenugreek has been traditionally used as an aphrodisiac, and its potential influence on testosterone levels may contribute to improvements in libido and sexual health.
- Improved Exercise Performance: Higher testosterone levels may be associated with increased exercise performance and muscle strength, making fenugreek an area of interest for athletes and those involved in physical fitness.
- Spermatogenesis Support: Testosterone plays a crucial role in spermatogenesis (sperm production), and fenugreek’s potential impact on testosterone levels may have implications for male reproductive health.
Mechanism of action
Mechanism of Action
Testosurge® is standardized to include a specific combination of steroidal and flavonoid glycosides. The steroidal glycosides in Testosurge® enhance the effectiveness of testosterone by competitively binding with SHBG. When testosterone is released into the bloodstream approximately 60-70% of it binds to SHBG. The steroidal glycosides from Testosurge® binds to SHBG and make testosterone free and bioavailable.
On the other hand, the flavonoid glycosides in Testosurge® play a role in increasing testosterone production. They achieve this by enhancing the expression of the steroidogenic acute regulatory (StAR) protein in Leydig cells. Testosterone is produced within the mitochondria of Leydig cells through steroidogenesis, where the StAR protein facilitates the entry of cholesterol into the mitochondrion.
Testosurge® has demonstrated inhibitory activity against5-alpha reductase and aromatase in cell line studies. 5-alpha reductase is an enzyme responsible for converting testosterone into DHT, while aromatase converts testosterone into Estrogen. This inhibition activity suggests that Testosurge® may help regulate the levels of these hormones in the body.
Additionally, Testosurge® can inhibit PDE5 enzyme which canresult in improved vasodilation and penile blood flow.
Efficacy
Efficacy
Human Clinical Study 1: Effects of Testosurge® supplementation on strength, body composition and hormonal profiles during an 8-week resistance training program.
Human Clinical Study 2: Effects of Single dose Testosurge® on serum testosterone levels of healthy sedentary male subjects
Scenario
Scenario
- Maximum oxygen uptake (VO2 max) is defined as the highest rate at which oxygen can be taken up and utilized by the body during severe exercise. It is one of the main variables in the field of exercise physiology and is frequently used to indicate the cardiorespiratory fitness of an individual.
- Research has shown that VO2 max may be a stronger predictor of future cardiac events, such as heart attacks, when compared to other established traditional risk factors including smoking, high blood pressure and type 2 diabetes. Therefore, higher levels of aerobic fitness are better.
- Knowing your VO2 max can help you measure fitness and heart health improvements over time. VO2 max is especially helpful for athletes like runners, swimmers, cross-country skiers, and rowers to guide their training.
Reference:
FOUNDATION
FOUNDATION
Fenugreek seed is known to significantly increase exercise performance by increasing endurance. The combined action of Glycosides, Trigonelline, and 4HI has a synergistic effect, enhancing endurance capacity, cardiorespiratory function, mental function, and energy production.
Endurance, both physical and mental, is multifaceted, involving cardiovascular efficiency, muscular strength, metabolic capacity, concentration, and stress management. These components collectively enable individuals to sustain prolonged physical activity and cope with challenges, demonstrating their ability to thrive across various aspects of life with both physical stamina and mental fortitude.
Studies suggest that fenugreek extract can boost endurance capacity and the use of fatty acids for energy. Recent research on fenugreek extract showed greater fat reduction compared to a placebo in young, healthy males engaged in resistance exercise. The glycogen-sparing effect of fenugreek extract is particularly beneficial during prolonged endurance exercise, as glycogen depletion leads to physical exhaustion, while slower glycogen utilization improves endurance performance.
Mechanism
of action
Mechanism of Action
Enducor™ achieves its effects through optimized parameters:
Enhanced Cardiac Function
Engaging in physical activity or exercise escalates the requirement for oxygen and nutrients within muscle cells and throughout the body. Enducor™ enhances the distribution of oxygen and nutrients to various body regions by notably augmenting cardiac output by increasing ejection fraction.
Improved Respiratory Function
The greater the oxygen utilization during intense workouts, the higher the energy generation, enabling extended maintenance of physical efforts. A person’s aerobic capacity, denoted as VO2 max, reflects the peak rate at which the heart, lungs, and muscles can effectively utilize oxygen throughout exercise.
Elevated Energy Production
Cellular respiration encompasses a series of metabolic processes within cells that convert acquired biochemical energy from food into adenosine triphosphate (ATP), a vital cellular energy compound. ATP serves as the cellular currency for energy exchange, with oxygen playing a crucial role in this process.
When oxygen is present, cells can convert a single glucose molecule into 38 ATPs through the citric acid pathway. In the absence of oxygen, cells adopt the lactic acid pathway, producing 2 ATPs. Oxygen’s significance extends to fat oxidation and ATP generation from fats.
Enducor enhances oxygen delivery to cells during exercise, achieved by boosting cardiac output and VO2 max. This improvement facilitates two key benefits: 1. Efficient generation of more ATPs from limited glucose, delaying glycogen depletion, and 2. Enabling the oxidation of free fatty acids to meet escalated energy demands during exercise.
Increased Mental Motivation
Dopamine and serotonin, often referred to as the “happy hormones,” play a pivotal role in modulating mood and driving motivation for both physical and mental endeavours.
Minimizes Muscle Soreness
Physical exercise prompts the body to release pro-inflammatory markers like cytokines, contributing to fatigue and muscle soreness. Enducor mitigates this effect by decreasing pro-inflammatory cytokines, leading to a reduction in muscle fatigue.
Efficacy
Efficacy
Human Clinical Study: Effects of 8 weeks of ENDUCOR supplementation in combination with exercise training on exercise capacity in healthy young volunteers.
Result: ENDUCOR Significantly increase endurance, metabolic parameters & respiratory exchange ratio (VO2 max, VO2-VT1, VO2-VT2, vVO2 max).