OVERVIEW
VARIANTS
OVERVIEW
VARIANTS
HEALTH BENEFITS
Helps in Weight management
Reduces body fat
Increases lean muscle mass
Increases strength
Benefits of weight management
USP
USP
SCIENCE
Mechanism
of action
Mechanism of Action
Activation of AMPK turns on ATP generating processes, while switching off ATP consuming processes in skeletal muscle, acute activation of AMPK increases glucose uptake and lipid oxidation, while chronic activation of AMPK is associated with mitochondrial biogenesis. Activation of AMPK inhibits glucose and lipid synthesis in the liver but increases lipid oxidation. Lipolysis and lipogenesis in adipose tissue are also reduced by AMPK activation. AMP activated protein kinase is a mediator of exercise induced signalling events in the regulation of GLUT 4 uptake in muscle.
Torabolic showed activation of AMPK and glucose transporter protein (GLUT4) in hepatocytes (liver cells) and adipocytes. It collectively showed to improve glucose uptake and increase lipid oxidation in muscle cells which further leads to increase in muscle strength and mass.
Torabolic showed significant increase in weight of levator ani (a skeletal muscle) without testosterone involvement in non-obese rats.
Multiple toxicology studies on Torabolic were conducted and it was found to be safe for long term consumption.Human clinical studies conducted on Torabolic in a double-blind placebo model, showed that Torabolic significantly increases muscle strength, reduces body fat percentage, and increases lean body muscle.
Efficacy
Efficacy
Human Clinical Study 1: Effects of Torabolic® supplementation on strength, body composition, power output and hormonal profiles in resistance-trained males.
Result: Torabolic significantly increased strength and lean muscle mass. Also, significantly reduced body fat percentage.
Human Clinical Study 2: A double-blind, placebo-controlled study investigating efficacy and safety of Torabolic® on various fat mass related parameters.
Result: Torabolic significantly decreased abdominal fat & percentage fat mass.
SCIENCE
Scenario
Scenario
- According to research, around 30% of overweight men have Testosterone Deficiency.
- 38% of men above 40 have testosterone levels below 300 ng/dl.
- Above the 80-year threshold, more than 50% of men have testosterone levels below 300 ng/dl.
- As far as diabetes patients go, up to 24% of men have low testosterone levels.
- Low T-levels are harmful for all aspects, including physical, mental, and social
Reference:
Foundation
Foundation
A broad spectrum of systematic reviews and scientific data demonstrated that fenugreek and its extracts improve glycemic and lipid profiles. Fenugreek is known to have antioxidant, anti-carcinogenic, gastro protective, anti-inflammatory, antimicrobial, immunological, anti-obesity, and hepatoprotective effects, and are beneficial to women’s health. Further, previous studies reported that fenugreek improved cognitive functions and Parkinson’s symptoms and showed anti anxiety, antidepressant, and neuroprotective properties. A recent study has reported the beneficial effects of fenugreek and its extract on hormonal-related statuses, such as galactagogue in lactating women and male impotence.
The presence of fenugreek seeds in various traditional medicinal systems is due to their composition of diverse phytochemicals, including Glycosides.
Potential benefits of fenugreek glycosides in testosterone production include: Increased Testosterone Levels:
- Fenugreek supplementation may lead to an increase in testosterone levels, which could have positive effects on muscle mass, strength, and overall vitality.
- Enhanced Libido: Fenugreek has been traditionally used as an aphrodisiac, and its potential influence on testosterone levels may contribute to improvements in libido and sexual health.
- Improved Exercise Performance: Higher testosterone levels may be associated with increased exercise performance and muscle strength, making fenugreek an area of interest for athletes and those involved in physical fitness.
- Spermatogenesis Support: Testosterone plays a crucial role in spermatogenesis (sperm production), and fenugreek’s potential impact on testosterone levels may have implications for male reproductive health.
Mechanism of action
Mechanism of Action
Testosurge® is standardized to include a specific combination of steroidal and flavonoid glycosides. The steroidal glycosides in Testosurge® enhance the effectiveness of testosterone by competitively binding with SHBG. When testosterone is released into the bloodstream approximately 60-70% of it binds to SHBG. The steroidal glycosides from Testosurge® binds to SHBG and make testosterone free and bioavailable.
On the other hand, the flavonoid glycosides in Testosurge® play a role in increasing testosterone production. They achieve this by enhancing the expression of the steroidogenic acute regulatory (StAR) protein in Leydig cells. Testosterone is produced within the mitochondria of Leydig cells through steroidogenesis, where the StAR protein facilitates the entry of cholesterol into the mitochondrion.
Testosurge® has demonstrated inhibitory activity against5-alpha reductase and aromatase in cell line studies. 5-alpha reductase is an enzyme responsible for converting testosterone into DHT, while aromatase converts testosterone into Estrogen. This inhibition activity suggests that Testosurge® may help regulate the levels of these hormones in the body.
Additionally, Testosurge® can inhibit PDE5 enzyme which canresult in improved vasodilation and penile blood flow.
Efficacy
Efficacy
Human Clinical Study 1: Effects of Testosurge® supplementation on strength, body composition and hormonal profiles during an 8-week resistance training program.
Result: 500 mg of daily Testosurge®supplementation significantly impacted Body Fat Percentage, Total Testosterone and Bioavailable Testosterone.
Human Clinical Study 2: Effects of Single dose Testosurge® on serum testosterone levels of healthy sedentary male subjects
Result: Single dose of Testosurge® significantly increased Free Testosterone, Bioavailable Testosterone, and Total Testosterone Levels after 10 hours of administration.
Scenario
Scenario
- Weight loss, achieved through a calorie-reduced diet, decreases both fat and fat-free (or lean body) mass.
- The contribution of fat-free mass loss often exceeds 35% of total weight loss for a person with normal weight.
- In persons who are overweight or obese, fat-free mass contributes 20–30% to total weight loss.
Reference:
FOUNDATION
FOUNDATION
Fenugreek, originating from the Mediterranean, Europe, and Asia, is highly valued in traditional medicine. Its seeds, known for their diverse benefits, add flavour to food and promote health. Used in Ayurveda and Chinese medicine, fenugreek aids digestion, heart health, and blood sugar regulation, making it versatile and beneficial across cultures.
Fenugreek seeds contain galactomannan, which is a secondary metabolite with well-documented scientific evidence demonstrating its effectiveness in aiding weight management while preserving lean muscle mass.
Mechanism
of action
Mechanism of Action
Activation of AMPK turns on ATP generating processes, while switching off ATP consuming processes in skeletal muscle, acute activation of AMPK increases glucose uptake and lipid oxidation, while chronic activation of AMPK is associated with mitochondrial biogenesis. Activation of AMPK inhibits glucose and lipid synthesis in the liver but increases lipid oxidation. Lipolysis and lipogenesis in adipose tissue are also reduced by AMPK activation. AMP activated protein kinase is a mediator of exercise induced signalling events in the regulation of GLUT 4 uptake in muscle.
Torabolic showed activation of AMPK and glucose transporter protein (GLUT4) in hepatocytes (liver cells) and adipocytes. It collectively showed to improve glucose uptake and increase lipid oxidation in muscle cells which further leads to increase in muscle strength and mass.
Torabolic showed significant increase in weight of levator ani (a skeletal muscle) without testosterone involvement in non-obese rats.
Multiple toxicology studies on Torabolic were conducted and it was found to be safe for long term consumption.Human clinical studies conducted on Torabolic in a double-blind placebo model, showed that Torabolic significantly increases muscle strength, reduces body fat percentage, and increases lean body muscle.
Efficacy
Efficacy
Human Clinical Study 1: Effects of Torabolic® supplementation on strength, body composition, power output and hormonal profiles in resistance-trained males.
Result: Torabolic significantly increased strength and lean muscle mass. Also, significantly reduced body fat percentage.
Human Clinical Study 2: A double-blind, placebo-controlled study investigating efficacy and safety of Torabolic® on various fat mass related parameters.
Result: Torabolic significantly decreased abdominal fat & percentage fat mass.
Certification
Certification
